STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYZPKS_ER domain-containing protein. (330 aa)    
Predicted Functional Partners:
NQO1
NAD(P)H quinone dehydrogenase 1.
  
  
 0.866
HMOX1
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
      
 0.678
KEAP1
Kelch like ECH associated protein 1.
   
  
 0.627
GCLC
Glutamate-cysteine ligase catalytic subunit.
      
 0.579
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.571
ENSCAFP00000048707
SCP2 domain-containing protein.
  
 0.571
ADHFE1
Alcohol dehydrogenase iron containing 1.
     
 0.569
FASN
Fatty acid synthase.
  
0.568
EPHX3
Epoxide hydrolase 3.
  
 0.556
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.552
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.