node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP1 | AQP2 | ENSCAFP00000043920 | ENSCAFP00000039918 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.589 |
AQP1 | AQP3 | ENSCAFP00000043920 | ENSCAFP00000050110 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Uncharacterized protein. | 0.729 |
AQP1 | AQP4 | ENSCAFP00000043920 | ENSCAFP00000026782 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.616 |
AQP1 | AQP8 | ENSCAFP00000043920 | ENSCAFP00000025764 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.664 |
AQP1 | AQP9 | ENSCAFP00000043920 | ENSCAFP00000024352 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.843 |
AQP1 | F1PXE0_CANLF | ENSCAFP00000043920 | ENSCAFP00000032136 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Uncharacterized protein. | 0.628 |
AQP1 | MIP | ENSCAFP00000043920 | ENSCAFP00000000190 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.569 |
AQP2 | AQP1 | ENSCAFP00000039918 | ENSCAFP00000043920 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | 0.589 |
AQP2 | AQP3 | ENSCAFP00000039918 | ENSCAFP00000050110 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein. | 0.718 |
AQP2 | AQP4 | ENSCAFP00000039918 | ENSCAFP00000026782 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.618 |
AQP2 | AQP8 | ENSCAFP00000039918 | ENSCAFP00000025764 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.643 |
AQP2 | AQP9 | ENSCAFP00000039918 | ENSCAFP00000024352 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.669 |
AQP2 | F1PXE0_CANLF | ENSCAFP00000039918 | ENSCAFP00000032136 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein. | 0.589 |
AQP2 | MIP | ENSCAFP00000039918 | ENSCAFP00000000190 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Lens fiber major intrinsic protein; Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity). Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.558 |
AQP3 | AQP1 | ENSCAFP00000050110 | ENSCAFP00000043920 | Uncharacterized protein. | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | 0.729 |
AQP3 | AQP2 | ENSCAFP00000050110 | ENSCAFP00000039918 | Uncharacterized protein. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.718 |
AQP3 | AQP4 | ENSCAFP00000050110 | ENSCAFP00000026782 | Uncharacterized protein. | Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.776 |
AQP3 | AQP8 | ENSCAFP00000050110 | ENSCAFP00000025764 | Uncharacterized protein. | Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.973 |
AQP3 | AQP9 | ENSCAFP00000050110 | ENSCAFP00000024352 | Uncharacterized protein. | Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.754 |
AQP3 | F1PXE0_CANLF | ENSCAFP00000050110 | ENSCAFP00000032136 | Uncharacterized protein. | Uncharacterized protein. | 0.666 |