STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (509 aa)    
Predicted Functional Partners:
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
    
 0.933
GNA11
Uncharacterized protein.
   
 0.771
GNA14
G protein subunit alpha 14.
    
 0.766
APOBR
Apolipoprotein B receptor.
  
   
 0.758
NCOA7
Nuclear receptor coactivator 7.
   
  
 0.742
HDC
Histidine decarboxylase.
      
 0.687
GPR3
G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.604
FOXJ2
Forkhead box J2.
      
 0.600
GNA15
G protein subunit alpha 15.
   
 0.589
HNMT
Histamine N-methyltransferase.
      
 0.573
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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