STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROB1Proline rich basic protein 1. (980 aa)    
Predicted Functional Partners:
SMIM33
Small integral membrane protein 33.
      
 0.527
SPATA24
Spermatogenesis associated 24.
      
 0.515
DNAJC18
DnaJ heat shock protein family (Hsp40) member C18.
    
 
 0.495
SLC23A1
Solute carrier family 23 member 1.
      
 0.489
ZNF518A
Zinc finger protein 518A.
  
 
   0.463
LRRTM2
Leucine rich repeat transmembrane neuronal 2.
    
 
 0.450
ECSCR
Endothelial cell-specific chemotaxis regulator; Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2 (By similarity).
      
 0.446
IRS4
Insulin receptor substrate 4.
  
 
   0.439
ZSWIM1
Zinc finger SWIM-type containing 1.
  
     0.404
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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