STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HS3ST6Sulfotransferase; Belongs to the sulfotransferase 1 family. (494 aa)    
Predicted Functional Partners:
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.481
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.463
GPC2
Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.463
GPC6
Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.463
GPC4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.463
AGRN
Agrin.
     
 0.453
GPC5
Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.445
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.445
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.415
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
  0.400
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.