STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MIS12Uncharacterized protein. (206 aa)    
Predicted Functional Partners:
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.974
NSL1
NSL1 component of MIS12 kinetochore complex.
   
 0.964
SPC24
SPC24 component of NDC80 kinetochore complex.
   
 0.868
NDC80
NDC80 kinetochore complex component.
   
 0.849
SPC25
SPC25 component of NDC80 kinetochore complex.
   
 0.835
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.828
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.755
J9P4J4_CANLF
Uncharacterized protein.
    
 
 0.742
ZWINT
ZW10 interacting kinetochore protein.
   
 
 0.725
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
 
 0.575
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.