STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-6NK2 homeobox 6. (307 aa)    
Predicted Functional Partners:
ZNF281
Zinc finger protein 281.
      
 0.507
ZBTB7B
Zinc finger and BTB domain containing 7B.
      
 0.486
GATA5
GATA binding protein 5.
   
 
 0.485
ZNF219
Zinc finger protein 219.
      
 0.485
KLF12
Kruppel like factor 12.
      
 0.484
TBX20
T-box transcription factor 20.
   
 
 0.467
ETV7
ETS variant 7.
    
 
 0.464
ETV3
ETS variant 3.
      
 0.460
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
      
 0.459
ZNF148
Zinc finger protein 148.
      
 0.454
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.