node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AK4 | AP1M1 | ENSCAFP00000027457 | ENSCAFP00000023182 | DnaJ heat shock protein family (Hsp40) member C6. | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | 0.616 |
AK4 | AP1S1 | ENSCAFP00000027457 | ENSCAFP00000022514 | DnaJ heat shock protein family (Hsp40) member C6. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.566 |
AK4 | CLINT1 | ENSCAFP00000027457 | ENSCAFP00000039849 | DnaJ heat shock protein family (Hsp40) member C6. | Clathrin interactor 1. | 0.667 |
AK4 | FTH1-2 | ENSCAFP00000027457 | ENSCAFP00000033829 | DnaJ heat shock protein family (Hsp40) member C6. | Ferritin heavy chain. | 0.528 |
AK4 | FTL | ENSCAFP00000027457 | ENSCAFP00000005761 | DnaJ heat shock protein family (Hsp40) member C6. | Ferritin light chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity); Belongs to the ferritin family. | 0.528 |
AK4 | SH3D19 | ENSCAFP00000027457 | ENSCAFP00000011866 | DnaJ heat shock protein family (Hsp40) member C6. | SH3 domain containing 19. | 0.576 |
AK4 | TFRC | ENSCAFP00000027457 | ENSCAFP00000019067 | DnaJ heat shock protein family (Hsp40) member C6. | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] | 0.504 |
AK4 | TGOLN2 | ENSCAFP00000027457 | ENSCAFP00000038403 | DnaJ heat shock protein family (Hsp40) member C6. | Uncharacterized protein. | 0.519 |
AP1M1 | AK4 | ENSCAFP00000023182 | ENSCAFP00000027457 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | DnaJ heat shock protein family (Hsp40) member C6. | 0.616 |
AP1M1 | AP1S1 | ENSCAFP00000023182 | ENSCAFP00000022514 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | 0.990 |
AP1M1 | CLINT1 | ENSCAFP00000023182 | ENSCAFP00000039849 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Clathrin interactor 1. | 0.618 |
AP1M1 | FTH1-2 | ENSCAFP00000023182 | ENSCAFP00000033829 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Ferritin heavy chain. | 0.534 |
AP1M1 | FTL | ENSCAFP00000023182 | ENSCAFP00000005761 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Ferritin light chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity); Belongs to the ferritin family. | 0.510 |
AP1M1 | SH3D19 | ENSCAFP00000023182 | ENSCAFP00000011866 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | SH3 domain containing 19. | 0.591 |
AP1M1 | TFRC | ENSCAFP00000023182 | ENSCAFP00000019067 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] | 0.544 |
AP1M1 | TGOLN2 | ENSCAFP00000023182 | ENSCAFP00000038403 | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Uncharacterized protein. | 0.660 |
AP1S1 | AK4 | ENSCAFP00000022514 | ENSCAFP00000027457 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | DnaJ heat shock protein family (Hsp40) member C6. | 0.566 |
AP1S1 | AP1M1 | ENSCAFP00000022514 | ENSCAFP00000023182 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | 0.990 |
AP1S1 | CLINT1 | ENSCAFP00000022514 | ENSCAFP00000039849 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Clathrin interactor 1. | 0.752 |
AP1S1 | FTH1-2 | ENSCAFP00000022514 | ENSCAFP00000033829 | AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. | Ferritin heavy chain. | 0.540 |