STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUFY4RUN and FYVE domain containing 4. (664 aa)    
Predicted Functional Partners:
ZNF142
Zinc finger protein 142.
      
 0.706
STK36
Serine/threonine kinase 36.
      
 0.676
TTLL7
Tubulin tyrosine ligase like 7.
      
 0.636
TMBIM1
Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family.
   
  
 0.568
ARPC2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
 
  
 
 0.524
VILL
Villin like.
    
 
 0.519
VIL1
Villin 1.
    
 
 0.519
RNF175
Ring finger protein 175.
      
 0.515
DYNLL2
Dynein light chain.
      
 0.495
SPPL2B
Signal peptide peptidase like 2B.
      
 0.491
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.