STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL15RAInterleukin 15 receptor subunit alpha. (251 aa)    
Predicted Functional Partners:
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
   
 
 0.995
IL-15L
Uncharacterized protein.
   
 
 0.864
IL2RB
Fibronectin type-III domain-containing protein.
   
 
 0.843
IL2RG
Cytokine receptor common subunit gamma; Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity). Belongs to the type I cytokine receptor family. Type 5 subfamily.
    
 
 0.838
ALG13
Uncharacterized protein.
    
 
 0.575
ALG13-2
Glyco_tran_28_C domain-containing protein.
    
 
 0.575
IL2RA
Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
 
 
  
 0.565
IL4R
Interleukin 4 receptor.
   
  
 0.516
PSME2
Proteasome activator subunit 2.
   
  
 0.503
IL27RA
Interleukin 27 receptor subunit alpha.
      
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.