STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RRBP1Ribosome-binding protein 1; Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. (1419 aa)    
Predicted Functional Partners:
SYNJ2BP
PDZ domain-containing protein.
    
 
 0.809
LEMD2
LEM domain containing 2.
   
 
 0.783
IGBP1
Immunoglobulin binding protein 1.
    
 
 0.733
SRPRB
SRP receptor subunit beta.
   
 
 0.711
CEP19
Centrosomal protein 19.
   
  
 0.682
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
    
 
 0.667
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
   
  
 0.664
SAR1A
Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.
   
  
 0.646
POLR3F
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.644
DEF8
Differentially expressed in FDCP 8 homolog.
      
 0.636
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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