Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHCY | ASIP | ENSCAFP00000011145 | ENSCAFP00000034367 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | 0.783 |
| AHCY | RALY | ENSCAFP00000011145 | ENSCAFP00000035261 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | RRM domain-containing protein. | 0.683 |
| ASIP | AHCY | ENSCAFP00000034367 | ENSCAFP00000011145 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.783 |
| ASIP | ATRN | ENSCAFP00000034367 | ENSCAFP00000009513 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Attractin. | 0.757 |
| ASIP | CBD103 | ENSCAFP00000034367 | ENSCAFP00000036690 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Uncharacterized protein. | 0.916 |
| ASIP | DCT | ENSCAFP00000034367 | ENSCAFP00000007942 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Uncharacterized protein. | 0.802 |
| ASIP | EDN3 | ENSCAFP00000034367 | ENSCAFP00000018044 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. | 0.706 |
| ASIP | GIMAP1 | ENSCAFP00000034367 | ENSCAFP00000006831 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | GTPase, IMAP family member 1. | 0.709 |
| ASIP | MITF | ENSCAFP00000034367 | ENSCAFP00000048192 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Melanocyte inducing transcription factor. | 0.746 |
| ASIP | RALY | ENSCAFP00000034367 | ENSCAFP00000035261 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | RRM domain-containing protein. | 0.723 |
| ASIP | STX17 | ENSCAFP00000034367 | ENSCAFP00000003700 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Syntaxin 17; Belongs to the syntaxin family. | 0.671 |
| ASIP | TYR | ENSCAFP00000034367 | ENSCAFP00000006504 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. Belongs to the tyrosinase family. | 0.872 |
| ATRN | ASIP | ENSCAFP00000009513 | ENSCAFP00000034367 | Attractin. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | 0.757 |
| ATRN | CBD103 | ENSCAFP00000009513 | ENSCAFP00000036690 | Attractin. | Uncharacterized protein. | 0.659 |
| CBD103 | ASIP | ENSCAFP00000036690 | ENSCAFP00000034367 | Uncharacterized protein. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | 0.916 |
| CBD103 | ATRN | ENSCAFP00000036690 | ENSCAFP00000009513 | Uncharacterized protein. | Attractin. | 0.659 |
| CBD103 | MITF | ENSCAFP00000036690 | ENSCAFP00000048192 | Uncharacterized protein. | Melanocyte inducing transcription factor. | 0.707 |
| CBD103 | RALY | ENSCAFP00000036690 | ENSCAFP00000035261 | Uncharacterized protein. | RRM domain-containing protein. | 0.455 |
| DCT | ASIP | ENSCAFP00000007942 | ENSCAFP00000034367 | Uncharacterized protein. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). | 0.802 |
| DCT | EDN3 | ENSCAFP00000007942 | ENSCAFP00000018044 | Uncharacterized protein. | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. | 0.689 |
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