STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT20Keratin 20; Belongs to the intermediate filament family. (434 aa)    
Predicted Functional Partners:
CCDC137
Coiled-coil domain containing 137.
    
 
 0.678
MMAB
Corrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 
 0.674
KRT82
Keratin 82; Belongs to the intermediate filament family.
   
0.658
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.649
ENSCAFP00000062374
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
0.639
KRT3
Keratin 3; Belongs to the intermediate filament family.
   
0.621
KRT81
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
0.619
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 
 0.609
QRFPR
Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.584
KRT6B
Keratin 75; Belongs to the intermediate filament family.
   
0.577
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.