STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB119Beta-defensin 119; Has antibacterial activity; Belongs to the beta-defensin family. (82 aa)    
Predicted Functional Partners:
DEFB125
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.830
DEFB124
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.817
MARCHF7
Membrane associated ring-CH-type finger 7.
      
 0.738
DEFB123
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.730
ASCC3
Activating signal cointegrator 1 complex subunit 3.
      
 0.714
UNC5C
Unc-5 netrin receptor C.
      
 0.714
DEFB1
Beta-defensin 1.
     
 0.714
DEFB129
Beta-defensin 129.
   
  
 0.713
HM13
Histocompatibility minor 13.
      
 0.707
DEFB136
Defensin beta 136.
     
 0.681
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.