STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F1PJW6_CANLFUncharacterized protein. (286 aa)    
Predicted Functional Partners:
E2R820_CANLF
DUF1968 domain-containing protein.
   
   0.738
F1PP29_CANLF
Uncharacterized protein.
  
   0.706
TRAV26-2
Ig-like domain-containing protein.
  
   0.641
F1PSQ5_CANLF
Uncharacterized protein.
   
   0.591
PTCRA
Pre T cell antigen receptor alpha.
    
   0.586
DLA-DRA
Ig-like domain-containing protein; Belongs to the MHC class II family.
    
   0.586
ENSCAFP00000057116
Ig-like domain-containing protein.
    
   0.586
CD3E
T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]
   
    0.546
IGHM
Ig mu chain C region.
  
   0.472
HLA-DQB2
Major histocompatibility complex, class II, DQ beta 1.
   
   0.459
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]