STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BNIP3LUncharacterized protein. (204 aa)    
Predicted Functional Partners:
GABARAPL2
GABA type A receptor associated protein like 2.
   
 0.945
GABARAPL1
GABA type A receptor associated protein like 1.
   
 0.941
STEAP3
STEAP3 metalloreductase.
   
 0.908
FUNDC1
FUN14 domain containing 1.
   
  
 0.747
BNIP3
BCL2 interacting protein 3.
  
 
 
0.667
PINK1
PTEN induced kinase 1.
   
 
 0.609
BCL2
Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).
   
 
 0.598
GABARAP
GABA type A receptor-associated protein.
   
 
 0.582
SQSTM1
Sequestosome 1.
    
 
 0.540
RAB9B
RAB9B, member RAS oncogene family.
   
  
 0.513
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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