STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC6Tetratricopeptide repeat domain 6. (600 aa)    
Predicted Functional Partners:
REC114
REC114 meiotic recombination protein.
      
 0.824
DNAAF4
Dynein axonemal assembly factor 4.
   
 
 0.819
STXBP6
Syntaxin binding protein 6.
      
 0.818
SLC44A4
Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family.
   
    0.805
SLC4A8
Anion exchange protein.
   
    0.805
CLBA1
Clathrin binding box of aftiphilin containing 1.
   
    0.805
FAM83B
Family with sequence similarity 83 member B.
      
 0.737
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.736
RNF144B
RBR-type E3 ubiquitin transferase.
      
 0.713
HCFC1
Host cell factor C1.
   
 
 0.684
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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