STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHRRAryl-hydrocarbon receptor repressor. (803 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
0.904
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
   
0.854
AIP
Peptidylprolyl isomerase.
    
 
 0.813
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
    
 
 0.710
CYP1A1
Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...]
    
 
 0.690
ANKRA2
Ankyrin repeat family A member 2.
   
 
 0.595
TIPARP
TCDD inducible poly(ADP-ribose) polymerase.
   
  
 0.583
MARCHF3
Membrane associated ring-CH-type finger 3.
   
  
 0.583
AIPL1
Aryl hydrocarbon receptor interacting protein like 1.
    
 
 0.581
RCOR1
REST corepressor 1.
      
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.