RALY protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

RALY

RRM domain-containing protein. (317 aa)

Predicted Functional Partners:

EIF2S2

0.809

ASIP

0.723

AHCY

0.683

CELF1

0.675

DENND1A

0.643

PRPF18

0.604

ITCH

0.587

EXOC2

0.587

RSRC1

0.555

SDK1

0.546

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHCY	ASIP	ENSCAFP00000011145	ENSCAFP00000034367	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	0.783
AHCY	EIF2S2	ENSCAFP00000011145	ENSCAFP00000011141	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	Eukaryotic translation initiation factor 2 subunit beta.	0.418
AHCY	ITCH	ENSCAFP00000011145	ENSCAFP00000011172	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	E3 ubiquitin-protein ligase.	0.713
AHCY	RALY	ENSCAFP00000011145	ENSCAFP00000035261	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	RRM domain-containing protein.	0.683
AHCY	SDK1	ENSCAFP00000011145	ENSCAFP00000023921	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	Sidekick cell adhesion molecule 1.	0.578
ASIP	AHCY	ENSCAFP00000034367	ENSCAFP00000011145	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	0.783
ASIP	EIF2S2	ENSCAFP00000034367	ENSCAFP00000011141	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	Eukaryotic translation initiation factor 2 subunit beta.	0.612
ASIP	ITCH	ENSCAFP00000034367	ENSCAFP00000011172	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	E3 ubiquitin-protein ligase.	0.650
ASIP	RALY	ENSCAFP00000034367	ENSCAFP00000035261	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	RRM domain-containing protein.	0.723
CELF1	RALY	ENSCAFP00000047830	ENSCAFP00000035261	CUGBP Elav-like family member 1.	RRM domain-containing protein.	0.675
DENND1A	RALY	ENSCAFP00000047183	ENSCAFP00000035261	DENN domain containing 1A.	RRM domain-containing protein.	0.643
EIF2S2	AHCY	ENSCAFP00000011141	ENSCAFP00000011145	Eukaryotic translation initiation factor 2 subunit beta.	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	0.418
EIF2S2	ASIP	ENSCAFP00000011141	ENSCAFP00000034367	Eukaryotic translation initiation factor 2 subunit beta.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	0.612
EIF2S2	EXOC2	ENSCAFP00000011141	ENSCAFP00000013512	Eukaryotic translation initiation factor 2 subunit beta.	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	0.609
EIF2S2	RALY	ENSCAFP00000011141	ENSCAFP00000035261	Eukaryotic translation initiation factor 2 subunit beta.	RRM domain-containing protein.	0.809
EIF2S2	RSRC1	ENSCAFP00000011141	ENSCAFP00000013093	Eukaryotic translation initiation factor 2 subunit beta.	Arginine and serine rich coiled-coil 1.	0.690
EXOC2	EIF2S2	ENSCAFP00000013512	ENSCAFP00000011141	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Eukaryotic translation initiation factor 2 subunit beta.	0.609
EXOC2	RALY	ENSCAFP00000013512	ENSCAFP00000035261	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	RRM domain-containing protein.	0.587
ITCH	AHCY	ENSCAFP00000011172	ENSCAFP00000011145	E3 ubiquitin-protein ligase.	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	0.713
ITCH	ASIP	ENSCAFP00000011172	ENSCAFP00000034367	E3 ubiquitin-protein ligase.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).	0.650