STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRHL1Grainyhead like transcription factor 1. (722 aa)    
Predicted Functional Partners:
ZNF333
Zinc finger protein 333.
    
 
 0.742
ATP6V1C2
V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
  
 0.690
ESRP1
Epithelial splicing regulatory protein 1.
   
  
 0.644
ESRP2
Epithelial splicing regulatory protein 2.
   
  
 0.618
ARHGAP29
Rho GTPase activating protein 29.
   
  
 0.529
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 
 0.512
ARHGEF10L
Rho guanine nucleotide exchange factor 10 like.
   
  
 0.512
SCRIB
Scribble planar cell polarity protein.
   
  
 0.489
PYROXD2
Pyridine nucleotide-disulphide oxidoreductase domain 2.
      
 0.487
ENAH
ENAH actin regulator.
    
 
 0.487
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.