STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKRIP1PRKR interacting protein 1. (186 aa)    
Predicted Functional Partners:
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
   
   0.824
CACTIN
Cactin, spliceosome C complex subunit.
   
 
 0.805
CDC40
Cell division cycle 40.
   
 
 0.740
SDE2
SDE2 telomere maintenance homolog.
    
 
 0.729
SLU7
SLU7 homolog, splicing factor.
   
 
 0.722
PRPF8
Pre-mRNA processing factor 8.
   
   0.720
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
   
   0.704
YJU2
YJU2 splicing factor homolog.
   
 
 0.703
CPNE2
Copine 2.
      
 0.702
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 
 0.695
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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