STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT222IF rod domain-containing protein; Belongs to the intermediate filament family. (295 aa)    
Predicted Functional Partners:
APLF
Aprataxin and PNKP like factor.
      
 0.855
TACO1
Translational activator of cytochrome c oxidase I.
    
 
 0.755
ENSCAFP00000060937
HMG box domain-containing protein.
 
 
  
 0.744
MRPL15
Mitochondrial ribosomal protein L15.
    
 
 0.729
ENSCAFP00000059928
HMG box domain-containing protein.
 
 
  
 0.713
MYBPC3
Myosin binding protein C, cardiac.
    
 
 0.686
DAG1
Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]
      
 0.678
ABHD3
Abhydrolase domain containing 3.
      
 0.668
ABHD1
Abhydrolase domain containing 1.
      
 0.668
ENSCAFP00000064778
Uncharacterized protein.
 
 
  
 0.660
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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