STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABI3ABI family member 3. (365 aa)    
Predicted Functional Partners:
GNGT2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.842
NCKAP1
NCK associated protein 1.
   
 
 0.825
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 
 0.824
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 
 0.771
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
 
 0.770
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
      
 0.749
TREM2
Triggering receptor expressed on myeloid cells 2.
      
 0.728
NCKAP1L
NCK associated protein 1 like.
   
 
 0.727
WASF3
WASP family member 3.
   
 
 0.714
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
      
 0.672
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.