STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (299 aa)    
Predicted Functional Partners:
UPRT
Uracil phosphoribosyltransferase homolog.
   
 0.851
TK1
Thymidine kinase.
  
 
 0.847
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
 0.839
DTYMK
Deoxythymidylate kinase.
  
 
 0.815
TYMS
Thymidylate synthetase.
  
 
 0.798
ENSCAFP00000050332
Thymidylat_synt domain-containing protein.
  
 
 0.798
MBD4
Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
      
 0.790
HDDC2
HD domain containing 2.
   
 
  0.773
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
  0.771
NAGS
N-acetylglutamate synthase.
    
  0.769
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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