STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1127 aa)    
Predicted Functional Partners:
MTREX
Mtr4 exosome RNA helicase.
    
 
 0.919
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.837
PPP2R2B
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
 
 0.837
IGFLR1
IGF like family receptor 1.
    
 
 0.794
CIR1
Corepressor interacting with RBPJ, 1.
      
 0.769
ZNFX1
Zinc finger NFX1-type containing 1.
      
 0.690
ZCCHC8
Zinc finger CCHC-type containing 8.
   
  
 0.673
ZFC3H1
Zinc finger C3H1-type containing.
      
 0.650
NOP53
NOP53 ribosome biogenesis factor.
      
 0.647
NABP1
Nucleic acid binding protein 1.
      
 0.644
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.