STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (526 aa)    
Predicted Functional Partners:
PDIA4
Protein disulfide isomerase family A member 4; Belongs to the protein disulfide isomerase family.
   
 0.965
P4HB
Protein disulfide-isomerase.
   
 0.954
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
 0.940
TXNDC5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
   
 0.937
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
  
 
0.926
ERP29
Endoplasmic reticulum protein 29.
   
 
 0.913
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 
 0.685
EDEM1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.655
HERPUD1
Homocysteine inducible ER protein with ubiquitin like domain 1.
   
  
 0.645
PDIA2
Protein disulfide isomerase family A member 2.
   
 
 0.572
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.