STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIPC2GIPC PDZ domain containing family member 2. (222 aa)    
Predicted Functional Partners:
ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; Belongs to the glycosyltransferase 29 family.
    
 
 0.845
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.822
HOXA1
Homeobox A1.
      
 0.787
CRIM1
Cysteine rich transmembrane BMP regulator 1.
   
  
 0.742
SLC44A5
Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family.
   
  
 0.738
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.719
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 
 0.719
CDC42EP2
Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.
      
 0.684
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
   
  
 0.677
AEBP2
AE binding protein 2.
      
 0.659
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.