STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHISA9Shisa family member 9. (424 aa)    
Predicted Functional Partners:
C5H1orf87
Chromosome 5 C1orf87 homolog.
      
 0.741
ZWINT
ZW10 interacting kinetochore protein.
      
 0.670
NLGN1
Neuroligin 1.
      
 0.521
GPR151
G protein-coupled receptor 151.
      
 0.514
TRDN
Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
      
 0.499
STK32B
Serine/threonine kinase 32B; Belongs to the protein kinase superfamily.
      
 0.489
SYNDIG1
Synapse differentiation inducing 1.
      
 0.485
GSG1L
GSG1 like.
      
 0.485
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.483
KCNH8
Potassium voltage-gated channel subfamily H member 8.
      
 0.449
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.