STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERICH5Uncharacterized protein. (55 aa)    
Predicted Functional Partners:
WDR37
WD repeat domain 37.
    
 
 0.704
LRRC45
Leucine rich repeat containing 45.
   
 
 0.665
PHACTR1
Phosphatase and actin regulator.
      
 0.625
ARMC8
Armadillo repeat containing 8.
    
 
 0.614
KTI12
KTI12 chromatin associated homolog.
      
 0.516
FAM126B
Family with sequence similarity 126 member B.
      
 0.515
KRT12
Keratin 12; Belongs to the intermediate filament family.
      
 0.502
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
    
 
 0.489
YME1L1
YME1 like 1 ATPase.
   
 
 0.428
LURAP1L
Leucine rich adaptor protein 1 like.
      
 0.412
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.