node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11H9orf72 | RAB39B | ENSCAFP00000002503 | ENSCAFP00000036618 | Chromosome 11 C9orf72 homolog. | RAB39B, member RAS oncogene family. | 0.907 |
C11H9orf72 | RAB8A | ENSCAFP00000002503 | ENSCAFP00000023207 | Chromosome 11 C9orf72 homolog. | Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] | 0.919 |
C11H9orf72 | SQSTM1 | ENSCAFP00000002503 | ENSCAFP00000065910 | Chromosome 11 C9orf72 homolog. | Sequestosome 1. | 0.699 |
C11H9orf72 | WDR41 | ENSCAFP00000002503 | ENSCAFP00000041138 | Chromosome 11 C9orf72 homolog. | WD repeat domain 41. | 0.994 |
GDI1 | GDI2 | ENSCAFP00000028963 | ENSCAFP00000007805 | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.464 |
GDI1 | RAB39B | ENSCAFP00000028963 | ENSCAFP00000036618 | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | RAB39B, member RAS oncogene family. | 0.586 |
GDI1 | RAB8A | ENSCAFP00000028963 | ENSCAFP00000023207 | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] | 0.798 |
GDI2 | GDI1 | ENSCAFP00000007805 | ENSCAFP00000028963 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | 0.464 |
GDI2 | RAB39B | ENSCAFP00000007805 | ENSCAFP00000036618 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | RAB39B, member RAS oncogene family. | 0.586 |
GDI2 | RAB8A | ENSCAFP00000007805 | ENSCAFP00000023207 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] | 0.803 |
GDI2 | RABGGTB | ENSCAFP00000007805 | ENSCAFP00000030242 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. | 0.522 |
ITSN1 | RAB39B | ENSCAFP00000062904 | ENSCAFP00000036618 | Intersectin 1. | RAB39B, member RAS oncogene family. | 0.568 |
ITSN2 | LOC100856635 | ENSCAFP00000006002 | ENSCAFP00000014017 | Intersectin 2. | Uncharacterized protein. | 0.623 |
ITSN2 | RAB39B | ENSCAFP00000006002 | ENSCAFP00000036618 | Intersectin 2. | RAB39B, member RAS oncogene family. | 0.603 |
LOC100856635 | ITSN2 | ENSCAFP00000014017 | ENSCAFP00000006002 | Uncharacterized protein. | Intersectin 2. | 0.623 |
LOC100856635 | RAB39B | ENSCAFP00000014017 | ENSCAFP00000036618 | Uncharacterized protein. | RAB39B, member RAS oncogene family. | 0.568 |
RAB39B | C11H9orf72 | ENSCAFP00000036618 | ENSCAFP00000002503 | RAB39B, member RAS oncogene family. | Chromosome 11 C9orf72 homolog. | 0.907 |
RAB39B | GDI1 | ENSCAFP00000036618 | ENSCAFP00000028963 | RAB39B, member RAS oncogene family. | Rab GDP dissociation inhibitor alpha; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. | 0.586 |
RAB39B | GDI2 | ENSCAFP00000036618 | ENSCAFP00000007805 | RAB39B, member RAS oncogene family. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.586 |
RAB39B | ITSN1 | ENSCAFP00000036618 | ENSCAFP00000062904 | RAB39B, member RAS oncogene family. | Intersectin 1. | 0.568 |