STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB40BRAB40B, member RAS oncogene family. (336 aa)    
Predicted Functional Partners:
WDR45B
WD repeat domain 45B.
 
 
  
 0.909
KCNH8
Potassium voltage-gated channel subfamily H member 8.
      
 0.783
ATP6V1B2
Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.
   
 
 0.719
TBC1D30
TBC1 domain family member 30.
    
 
 0.695
RILPL2
Rab interacting lysosomal protein like 2.
    
 
 0.684
KCNH1
Potassium voltage-gated channel subfamily H member 1.
   
  
 0.679
ADRA2C
Adrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.674
ZNF513
Zinc finger protein 513.
   
 
 0.665
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.645
LYPD6
LY6/PLAUR domain containing 6.
   
 
 0.628
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.