STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUSP13Dual specificity phosphatase 13; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (376 aa)    
Predicted Functional Partners:
AP3M1
AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.
   
 
 0.891
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.891
MRM1
Mitochondrial rRNA methyltransferase 1.
   
  
 0.676
TPPP
Tubulin polymerization promoting protein.
   
  
 0.570
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
   
  
 0.536
SAMD8
Sterile alpha motif domain containing 8.
      
 0.510
SMIM12
Small integral membrane protein 12.
   
 
 0.450
UTP15
UTP15 small subunit processome component.
   
  
 0.432
KRT36
Keratin 36; Belongs to the intermediate filament family.
   
 
 0.427
ALPK3
Alpha kinase 3.
   
  
 0.417
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.