STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)    
Predicted Functional Partners:
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
  
0.828
GRIK5
Uncharacterized protein.
  
 
0.812
GRM2
Glutamate metabotropic receptor 2.
   
  
 0.720
PLAC8L1
PLAC8 like 1.
      
 0.693
CSMD2
Uncharacterized protein.
   
  
 0.675
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 
 0.657
GJA9
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.647
TCTN1
Tectonic family member 1.
      
 0.636
FAM172A
Family with sequence similarity 172 member A.
      
 0.617
DLG1
Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.
   
 0.605
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.