HDAC1 protein (Canis lupus familiaris) - STRING interaction network

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HDAC1

Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (508 aa)

Predicted Functional Partners:

CHD4

0.981

RB1

0.974

PTPN9

0.965

HDAC2

0.958

SAP30

0.950

RBBP7

0.944

IRF1

0.943

RCOR1

0.941

RBPJ

0.932

NCOR2

0.925

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD4	HDAC1	ENSCAFP00000022067	ENSCAFP00000036819	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.981
CHD4	HDAC2	ENSCAFP00000022067	ENSCAFP00000042408	Chromodomain helicase DNA binding protein 4.	Histone deacetylase 2.	0.969
CHD4	IRF1	ENSCAFP00000022067	ENSCAFP00000001223	Chromodomain helicase DNA binding protein 4.	Interferon regulatory factor 1.	0.908
CHD4	PTPN9	ENSCAFP00000022067	ENSCAFP00000042090	Chromodomain helicase DNA binding protein 4.	SIN3 transcription regulator family member A.	0.457
CHD4	RBBP7	ENSCAFP00000022067	ENSCAFP00000018764	Chromodomain helicase DNA binding protein 4.	RB binding protein 7, chromatin remodeling factor.	0.887
CHD4	RCOR1	ENSCAFP00000022067	ENSCAFP00000026701	Chromodomain helicase DNA binding protein 4.	REST corepressor 1.	0.702
CHD4	SAP30	ENSCAFP00000022067	ENSCAFP00000011613	Chromodomain helicase DNA binding protein 4.	Sin3A associated protein 30.	0.604
HDAC1	CHD4	ENSCAFP00000036819	ENSCAFP00000022067	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Chromodomain helicase DNA binding protein 4.	0.981
HDAC1	HDAC2	ENSCAFP00000036819	ENSCAFP00000042408	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.958
HDAC1	IRF1	ENSCAFP00000036819	ENSCAFP00000001223	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Interferon regulatory factor 1.	0.943
HDAC1	NCOR2	ENSCAFP00000036819	ENSCAFP00000010374	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 2.	0.925
HDAC1	PTPN9	ENSCAFP00000036819	ENSCAFP00000042090	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	SIN3 transcription regulator family member A.	0.965
HDAC1	RB1	ENSCAFP00000036819	ENSCAFP00000057502	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RB transcriptional corepressor 1.	0.974
HDAC1	RBBP7	ENSCAFP00000036819	ENSCAFP00000018764	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RB binding protein 7, chromatin remodeling factor.	0.944
HDAC1	RBPJ	ENSCAFP00000036819	ENSCAFP00000064615	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Recombination signal binding protein for immunoglobulin kappa J region.	0.932
HDAC1	RCOR1	ENSCAFP00000036819	ENSCAFP00000026701	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 1.	0.941
HDAC1	SAP30	ENSCAFP00000036819	ENSCAFP00000011613	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sin3A associated protein 30.	0.950
HDAC2	CHD4	ENSCAFP00000042408	ENSCAFP00000022067	Histone deacetylase 2.	Chromodomain helicase DNA binding protein 4.	0.969
HDAC2	HDAC1	ENSCAFP00000042408	ENSCAFP00000036819	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.958
HDAC2	IRF1	ENSCAFP00000042408	ENSCAFP00000001223	Histone deacetylase 2.	Interferon regulatory factor 1.	0.943

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