STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM216AFamily with sequence similarity 216 member A. (254 aa)    
Predicted Functional Partners:
PPTC7
Protein phosphatase; Belongs to the PP2C family.
      
 0.612
GPN3
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
  
 0.584
HVCN1
Hydrogen voltage gated channel 1.
      
 0.563
CCDC63
Coiled-coil domain containing 63.
      
 0.526
ANAPC7
Anaphase promoting complex subunit 7.
      
 0.515
RAD9B
Cell cycle checkpoint control protein; Belongs to the rad9 family.
      
 0.515
SMYD4
SET and MYND domain containing 4.
      
 0.515
NKTR
Natural killer cell triggering receptor.
      
 0.515
MED29
Mediator complex subunit 29.
      
 0.512
TCTN1
Tectonic family member 1.
      
 0.503
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.