PTPRJ protein (Canis lupus familiaris) - STRING interaction network

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Score

PTPRJ

Protein tyrosine phosphatase receptor type J. (1229 aa)

Predicted Functional Partners:

CTNND1

0.944

MET

0.816

FLT3

0.800

PASK

0.782

FLT3LG

0.762

HGF

0.753

PIANP

0.673

KNSTRN

0.560

SSX2IP

0.553

CDH5

0.533

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH5	CTNND1	ENSCAFP00000030279	ENSCAFP00000011503	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Catenin delta 1.	0.965
CDH5	PTPRJ	ENSCAFP00000030279	ENSCAFP00000036908	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type J.	0.533
CTNND1	CDH5	ENSCAFP00000011503	ENSCAFP00000030279	Catenin delta 1.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.965
CTNND1	MET	ENSCAFP00000011503	ENSCAFP00000041478	Catenin delta 1.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.931
CTNND1	PTPRJ	ENSCAFP00000011503	ENSCAFP00000036908	Catenin delta 1.	Protein tyrosine phosphatase receptor type J.	0.944
CTNND1	SSX2IP	ENSCAFP00000011503	ENSCAFP00000030115	Catenin delta 1.	SSX family member 2 interacting protein.	0.478
FLT3	FLT3LG	ENSCAFP00000051387	ENSCAFP00000055324	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fms related tyrosine kinase 3 ligand.	0.968
FLT3	HGF	ENSCAFP00000051387	ENSCAFP00000009539	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	0.720
FLT3	PTPRJ	ENSCAFP00000051387	ENSCAFP00000036908	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Protein tyrosine phosphatase receptor type J.	0.800
FLT3LG	FLT3	ENSCAFP00000055324	ENSCAFP00000051387	Fms related tyrosine kinase 3 ligand.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.968
FLT3LG	PTPRJ	ENSCAFP00000055324	ENSCAFP00000036908	Fms related tyrosine kinase 3 ligand.	Protein tyrosine phosphatase receptor type J.	0.762
HGF	FLT3	ENSCAFP00000009539	ENSCAFP00000051387	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.720
HGF	MET	ENSCAFP00000009539	ENSCAFP00000041478	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.998
HGF	PTPRJ	ENSCAFP00000009539	ENSCAFP00000036908	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	Protein tyrosine phosphatase receptor type J.	0.753
KNSTRN	PTPRJ	ENSCAFP00000013391	ENSCAFP00000036908	Kinetochore localized astrin (SPAG5) binding protein.	Protein tyrosine phosphatase receptor type J.	0.560
MET	CTNND1	ENSCAFP00000041478	ENSCAFP00000011503	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Catenin delta 1.	0.931
MET	HGF	ENSCAFP00000041478	ENSCAFP00000009539	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily.	0.998
MET	PTPRJ	ENSCAFP00000041478	ENSCAFP00000036908	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Protein tyrosine phosphatase receptor type J.	0.816
PASK	PTPRJ	ENSCAFP00000018915	ENSCAFP00000036908	PAS domain containing serine/threonine kinase.	Protein tyrosine phosphatase receptor type J.	0.782
PIANP	PTPRJ	ENSCAFP00000021701	ENSCAFP00000036908	PILR alpha associated neural protein.	Protein tyrosine phosphatase receptor type J.	0.673