STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (842 aa)    
Predicted Functional Partners:
EED
Embryonic ectoderm development.
   
 0.999
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.999
JARID2
Jumonji and AT-rich interaction domain containing 2.
   
 0.989
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.978
AEBP2
AE binding protein 2.
   
 0.971
PHF1
PHD finger protein 1.
   
 0.961
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.926
ENSCAFP00000058271
WD_REPEATS_REGION domain-containing protein.
   
 0.922
MTF2
Metal response element binding transcription factor 2.
   
 0.918
DNMT3A
DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.908
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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