STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES4Hes family bHLH transcription factor 4. (259 aa)    
Predicted Functional Partners:
FANCL
FA complementation group L.
    
 
 0.827
FANCG
FA complementation group G.
   
 
 0.826
FANCF
FA complementation group F.
    
 
 0.825
FANCA
FA complementation group A.
    
 
 0.823
FANCC
FA complementation group C.
   
   0.813
ISM1
Isthmin 1.
      
 0.674
TLE4
TLE family member 4, transcriptional corepressor.
   
 
 0.611
TLE1
TLE family member 1, transcriptional corepressor.
    
 
 0.610
TLE2
TLE family member 2, transcriptional corepressor.
    
 
 0.610
F1Q3N3_CANLF
WD_REPEATS_REGION domain-containing protein.
    
 
 0.610
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.