STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)    
Predicted Functional Partners:
LOC475563
UBIQUITIN_CONJUGAT_2 domain-containing protein.
  
  
 
0.901
UBE2E3
Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.
  
  
 
0.900
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 0.845
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.781
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
   
 0.701
ENSCAFP00000047437
Uncharacterized protein.
   
 
 0.696
UBA6
Ubiquitin like modifier activating enzyme 6.
   
 0.686
ENSCAFP00000053186
annotation not available
   
 
 0.685
UBE2Q1
Ubiquitin conjugating enzyme E2 Q1.
   
 
 0.679
UBA52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]
   
 0.674
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.