STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM176BTransmembrane protein 176B. (328 aa)    
Predicted Functional Partners:
TMEM176A
Transmembrane protein 176A.
   
 
0.929
CHIC2
Cysteine rich hydrophobic domain 2.
      
 0.577
PDE7B
Phosphodiesterase.
    
 
 0.563
ZNF775
Uncharacterized protein.
    
 
 0.558
PAFAH2
Platelet-activating factor acetylhydrolase.
      
 0.546
CPXM1
Carboxypeptidase X, M14 family member 1.
   
  
 0.529
RIOK3
Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.
   
  
 0.513
MTREX
Mtr4 exosome RNA helicase.
   
 
 0.505
MPZL3
Myelin protein zero like 3.
      
 0.487
ACSS3
Acyl-CoA synthetase short chain family member 3.
   
  
 0.482
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.