STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLCD5TLC domain containing 5. (383 aa)    
Predicted Functional Partners:
LOXL1
Lysyl oxidase like 1.
      
 0.733
RBMS3
RNA binding motif single stranded interacting protein 3.
      
 0.679
SORBS2
Sorbin and SH3 domain containing 2.
      
 0.665
TNIK
TRAF2 and NCK interacting kinase.
      
 0.626
RBFOX1
RNA binding fox-1 homolog 1.
      
 0.578
SSH3
Slingshot protein phosphatase 3.
      
 0.563
FGF14
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.529
ARHGEF12
Rho guanine nucleotide exchange factor 12.
      
 0.523
AGPAT1
1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
      
 0.523
FMN1
Formin 1.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.