STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEMD3LEM domain containing 3. (448 aa)    
Predicted Functional Partners:
SMAD1
Mothers against decapentaplegic homolog.
   
 
 0.889
WIF1
WNT inhibitory factor 1.
      
 0.804
SMAD2
Mothers against decapentaplegic homolog.
   
 
 0.800
MSRB3
Methionine sulfoxide reductase B3.
      
 0.785
SMAD3
Mothers against decapentaplegic homolog.
   
 
 0.768
CDC5L
Cell division cycle 5 like.
   
 
 0.730
TMBIM4
Uncharacterized protein; Belongs to the BI1 family.
      
 0.695
MGAT1
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
      
 0.687
SREK1
Splicing regulatory glutamic acid and lysine rich protein 1.
   
 
 0.687
TBC1D30
TBC1 domain family member 30.
      
 0.672
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.