STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDAEctodysplasin A isoform EDA-A2; Belongs to the tumor necrosis factor family. (386 aa)    
Predicted Functional Partners:
EDAR
Ectodysplasin A receptor.
   
 0.963
LRRC9
Leucine rich repeat containing 9.
   
  
 0.817
EDARADD
EDAR associated death domain.
     
 0.780
AFAP1L1
Actin filament associated protein 1 like 1.
      
 0.560
TRIM14
Tripartite motif containing 14.
      
 0.506
SBF1
SET binding factor 1.
      
 0.506
PITX1
Homeobox protein.
   
  
 0.505
CLINT1
Clathrin interactor 1.
      
 0.485
TRIM35
Tripartite motif containing 35.
   
  
 0.464
ARHGEF3
Rho guanine nucleotide exchange factor 3.
      
 0.453
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.