STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL4A6Collagen type IV alpha 6 chain. (1707 aa)    
Predicted Functional Partners:
COL4A5
Collagen alpha-5(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
  
0.912
GP6
Glycoprotein VI platelet.
   
 
 0.910
PELO
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
    
 0.835
COL21A1
Collagen type XXI alpha 1 chain.
  
 
0.785
ITGA3
Integrin subunit alpha 3; Belongs to the integrin alpha chain family.
    
 0.780
ITGA10
Integrin subunit alpha 10; Belongs to the integrin alpha chain family.
   
 0.774
COL14A1
Collagen type XIV alpha 1 chain.
  
0.752
ITGA7
Integrin subunit alpha 7; Belongs to the integrin alpha chain family.
    
 0.752
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.750
ITGA6
Integrin subunit alpha 6; Belongs to the integrin alpha chain family.
    
 0.750
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.