STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPEPL1Aminopeptidase like 1. (509 aa)    
Predicted Functional Partners:
UQCRFS1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
   
 
  0.770
RNF145
Ring finger protein 145.
      
 0.769
STX16
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
 
 
  
 0.731
PRPF19
Pre-mRNA processing factor 19.
   
 
 0.724
NKAPL
NFKB activating protein like.
      
 0.703
USP39
Ubiquitin specific peptidase 39.
      
 0.677
MMP25
Matrix metallopeptidase 25.
      
 0.677
C24H20orf85
Chromosome 24 C20orf85 homolog.
      
 0.653
HIPK3
Homeodomain interacting protein kinase 3.
    
 
 0.642
NCOA5
Nuclear receptor coactivator 5.
      
 0.642
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.