STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD22Ankyrin repeat domain 22. (191 aa)    
Predicted Functional Partners:
ZNF831
Zinc finger protein 831.
    
 
 0.791
SLC6A15
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.790
CBX5
Chromobox 5.
    
 
 0.756
PLLP
Plasmolipin.
      
 0.708
WDR5B
WD repeat domain 5B.
    
 
 0.685
BLK
Tyrosine-protein kinase.
   
 
 0.684
TMEM156
Transmembrane protein 156.
      
 0.676
SLITRK6
SLIT and NTRK like family member 6.
   
 
 0.669
PTPRZ1
Protein tyrosine phosphatase receptor type Z1.
    
 
 0.598
IFI44
Interferon induced protein 44.
   
 
 0.566
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.