STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAGN1Jagunal homolog 1. (183 aa)    
Predicted Functional Partners:
GNB1L
G protein subunit beta 1 like.
   
  
 0.936
SCAMP2
Secretory carrier-associated membrane protein.
   
 
 0.806
SEC61A1
Protein transport protein Sec61 subunit alpha isoform 1.
   
 
 0.762
ITM2B
Integral membrane protein 2B.
      
 0.682
SYNPR
Synaptoporin.
      
 0.676
SEC61A2
Protein transport protein Sec61 subunit alpha isoform 1; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post- translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC [...]
   
 
 0.674
GPR37
G protein-coupled receptor 37.
   
  
 0.673
VPS45
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.672
ELANE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
      
 0.672
G6PC3
Glucose-6-phosphatase catalytic subunit 3.
   
  
 0.586
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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