STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYYR1Cysteine and tyrosine rich 1. (172 aa)    
Predicted Functional Partners:
SLC4A11
Solute carrier family 4 member 11.
      
 0.862
COL8A2
Collagen type VIII alpha 2 chain.
   
  
 0.746
PKP3
Plakophilin 3.
      
 0.603
HSPB6
Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.583
TCF21
Transcription factor 21.
   
  
 0.557
CLDN14
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.552
CLEC14A
C-type lectin domain containing 14A.
   
  
 0.552
CD200
CD200 molecule.
   
  
 0.535
ZP4
Zona pellucida glycoprotein 4.
      
 0.515
TMED6
GOLD domain-containing protein.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.