STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REM1RRAD and GEM like GTPase 1. (486 aa)    
Predicted Functional Partners:
CCT6B
Chaperonin containing TCP1 subunit 6B.
   
 
 0.810
SNTA1
Syntrophin alpha 1.
   
  
 0.771
TP53BP1
Tumor protein p53 binding protein 1.
      
 0.648
ITSN2
Intersectin 2.
   
 
 0.606
AFDN
Afadin, adherens junction formation factor.
    
 
 0.585
LOC100856635
Uncharacterized protein.
    
 
 0.568
ITSN1
Intersectin 1.
    
 
 0.568
SHANK1
SH3 and multiple ankyrin repeat domains 1.
   
 
 0.562
J9PBG9_CANLF
PDZ domain-containing protein.
   
 
 0.556
HEG1
Heart development protein with EGF like domains 1.
   
 
 0.543
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.