ITFG2 protein (Canis lupus familiaris) - STRING interaction network

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Score

ITFG2

Integrin alpha FG-GAP repeat containing 2. (487 aa)

Predicted Functional Partners:

KPTN

0.999

C10H12orf66

0.995

DEPDC5

0.987

NPRL2

0.985

WDR24

0.981

WDR59

0.981

LAMP1

0.930

BMT2

0.888

SZT2

0.800

SESN2

0.784

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C10H12orf66	ENSCAFP00000039384	ENSCAFP00000040219	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 10 C12orf66 homolog.	0.843
BMT2	DEPDC5	ENSCAFP00000039384	ENSCAFP00000050074	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain containing 5.	0.845
BMT2	ITFG2	ENSCAFP00000039384	ENSCAFP00000037823	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Integrin alpha FG-GAP repeat containing 2.	0.888
BMT2	KPTN	ENSCAFP00000039384	ENSCAFP00000006107	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin, actin binding protein.	0.817
BMT2	NPRL2	ENSCAFP00000039384	ENSCAFP00000015575	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.747
BMT2	SESN2	ENSCAFP00000039384	ENSCAFP00000042218	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Sestrin 2.	0.670
BMT2	SZT2	ENSCAFP00000039384	ENSCAFP00000061292	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	SZT2 subunit of KICSTOR complex.	0.499
C10H12orf66	BMT2	ENSCAFP00000040219	ENSCAFP00000039384	Chromosome 10 C12orf66 homolog.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.843
C10H12orf66	DEPDC5	ENSCAFP00000040219	ENSCAFP00000050074	Chromosome 10 C12orf66 homolog.	DEP domain containing 5.	0.991
C10H12orf66	ITFG2	ENSCAFP00000040219	ENSCAFP00000037823	Chromosome 10 C12orf66 homolog.	Integrin alpha FG-GAP repeat containing 2.	0.995
C10H12orf66	KPTN	ENSCAFP00000040219	ENSCAFP00000006107	Chromosome 10 C12orf66 homolog.	Kaptin, actin binding protein.	0.995
C10H12orf66	NPRL2	ENSCAFP00000040219	ENSCAFP00000015575	Chromosome 10 C12orf66 homolog.	NPR2 like, GATOR1 complex subunit.	0.990
C10H12orf66	SESN2	ENSCAFP00000040219	ENSCAFP00000042218	Chromosome 10 C12orf66 homolog.	Sestrin 2.	0.542
C10H12orf66	SZT2	ENSCAFP00000040219	ENSCAFP00000061292	Chromosome 10 C12orf66 homolog.	SZT2 subunit of KICSTOR complex.	0.800
C10H12orf66	WDR24	ENSCAFP00000040219	ENSCAFP00000029025	Chromosome 10 C12orf66 homolog.	WD repeat domain 24.	0.985
C10H12orf66	WDR59	ENSCAFP00000040219	ENSCAFP00000057181	Chromosome 10 C12orf66 homolog.	WD repeat domain 59.	0.982
DEPDC5	BMT2	ENSCAFP00000050074	ENSCAFP00000039384	DEP domain containing 5.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.845
DEPDC5	C10H12orf66	ENSCAFP00000050074	ENSCAFP00000040219	DEP domain containing 5.	Chromosome 10 C12orf66 homolog.	0.991
DEPDC5	ITFG2	ENSCAFP00000050074	ENSCAFP00000037823	DEP domain containing 5.	Integrin alpha FG-GAP repeat containing 2.	0.987
DEPDC5	KPTN	ENSCAFP00000050074	ENSCAFP00000006107	DEP domain containing 5.	Kaptin, actin binding protein.	0.989